1H-Indole-3-carboxiMidaMide, N-hydroxy-5-Methoxy-

1H-Indole-3-carboxiMidaMide, N-hydroxy-5-Methoxy- - Names and Identifiers

Name	N'-hydroxy-5-methoxy-1H-indole-3-carboxamidine
Synonyms	N-HYDROXY-5-METHOXY-1H-INDOLE-3-CARBOXAMIDINE N'-hydroxy-5-methoxy-1H-indole-3-carboxamidine N-hydroxy-5-methoxy-1H-indole-3-carboximidamide N'-hydroxy-5-Methoxy-1H-indole-3-carboxiMidaMide 1H-Indole-3-carboxiMidaMide, N-hydroxy-5-Methoxy- (Z)-N'-hydroxy-5-Methoxy-1H-indole-3-carboxaMidine 1H-indole-3-carboximidamide, N'-hydroxy-5-methoxy-
CAS	889943-79-7
InChI	InChI=1/C10H11N3O2/c1-15-6-2-3-9-7(4-6)8(5-12-9)10(11)13-14/h2-5,12,14H,1H3,(H2,11,13)

1H-Indole-3-carboxiMidaMide, N-hydroxy-5-Methoxy- - Physico-chemical Properties

Molecular Formula	C10H11N3O2
Molar Mass	205.21
Density	1.40±0.1 g/cm3(Predicted)
Boling Point	431.1±48.0 °C(Predicted)
Flash Point	252.3°C
Vapor Presure	1.47E-10mmHg at 25°C
pKa	6.92±0.69(Predicted)
Storage Condition	2-8°C
Refractive Index	1.657

1H-Indole-3-carboxiMidaMide, N-hydroxy-5-Methoxy- - Introduction

N'-hydroxy-5-methoxy-1H-indole-3-carboxamidine(N'-hydroxy-5-methoxy-1H-indole-3-carboxamidine) is an organic compound with the following properties:

Appearance: solid powder
Molecular formula: C11H12N4O2
Molecular weight: 236.24g/mol
Melting point: about 175-178°C
Solubility: insoluble in water, soluble in organic solvents such as methanol

The main uses of N'-hydroxy-5-methoxy-1H-indole-3-carboxamidine include as reagents and intermediates in organic synthesis. It is commonly used in the synthesis of drugs and other biologically active compounds. Because its molecule contains indole skeleton and amidino (amidine) functional groups, it can participate in a variety of chemical reactions, such as nucleophilic substitution reaction, amination reaction and amidation reaction.

N'-hydroxy-5-methoxy-1H-indole-3-carboxamidine can be synthesized by the following methods: First, methyl and hydroxyl groups are introduced on indole through a nucleophilic substitution reaction to form 5-methoxy-1-H-indole. Then, a carbamidine group was introduced on the 5-methoxy-1-H-indole by an amidination reaction. Finally, a carbamimidoyl group was introduced on the N'-hydroxy-5-methoxy-1-H-indole-3-carboxamidine.

For safety information, there are currently limited studies on the toxicity and harmfulness of N'-hydroxy-5-methoxy-1H-indole-3-carboxamidine. However, as an organic compound, it should be used in accordance with normal safe practices, such as wearing appropriate protective equipment (such as gloves, goggles and laboratory coats) and ensuring that the operation is carried out under well-ventilated conditions. At the same time, you should beware of contact with skin, eyes and respiratory tract. If you accidentally splash in, please rinse with water immediately and seek medical assistance. When using this compound, a suitable risk assessment should be carried out according to the specific experimental conditions and purposes, and correct waste disposal methods should be followed.

Last Update：2024-04-09 21:11:58